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##  29 results 

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### Forthcoming

Avik Mukherjee, Yanqing Huang, Seungeun Oh, Carlos Sanchez, Yu-Fang Chang, Xili Liu, Gary Andrew Bradshaw, Nina Catherine Benites, Johan Paulsson, Marc W. Kirschner, Yongjin Sung, Jens Elgeti, and Markus Basan. “[A Universal Mechanism of Biomass Density Homeostasis via Ribosomal Counterions](https://www.biorxiv.org/content/10.1101/2023.08.31.555748v5)”



 

 

Avik Mukherjee, Yanqing Huang, Seungeun Oh, Carlos Sanchez, Yu-Fang Chang, Xili Liu, Gary Andrew Bradshaw, Nina Catherine Benites, Johan Paulsson, Marc W. Kirschner, Yongjin Sung, Jens Elgeti, and Markus Basan. “[A Universal Mechanism of Biomass Density Homeostasis via Ribosomal Counterions](https://www.biorxiv.org/content/10.1101/2023.08.31.555748v5)”



 

 

 

 

 



### 2026

Avik Mukherjee, Yanqing Huang, Jens Elgeti, Seungeun Oh, Dan-Dan Su, Christophe Dupre, Nina Catherine Benites, Xili Liu, Leonid Peshkin, Mihail Barboiu, Hugo Stocker, Marc W Kirschner, and Markus Basan. 2026. “[Membrane Potential Mediates the Cellular Response to Mechanical Pressure](https://www.cell.com/cell/abstract/S0092-8674(25)01253-X?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS009286742501253X%3Fshowall%3Dtrue)”. Cell, 189, 1, Pp. 17. doi:10.1016/j.cell.2025.11.004



 

 

Avik Mukherjee, Yanqing Huang, Jens Elgeti, Seungeun Oh, Dan-Dan Su, Christophe Dupre, Nina Catherine Benites, Xili Liu, Leonid Peshkin, Mihail Barboiu, Hugo Stocker, Marc W Kirschner, and Markus Basan. 2026. “[Membrane Potential Mediates the Cellular Response to Mechanical Pressure](https://www.cell.com/cell/abstract/S0092-8674(25)01253-X?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS009286742501253X%3Fshowall%3Dtrue)”. Cell, 189, 1, Pp. 17. doi:10.1016/j.cell.2025.11.004



 

 

 

- [ descriptionPublisher's Version](https://www.cell.com/cell/abstract/S0092-8674(25)01253-X)
 
- [ descriptionPublisher's Version](https://www.cell.com/cell/abstract/S0092-8674(25)01253-X)
 
 

 



### 2024

Avik Mukherjee, Yu-Fang Chang, Yanqing Huang, Jade Ealy, Mark Polk, and Markus Basan. 2024. “[Plasticity of Growth Laws Tunes Resource Allocation Strategies in Bacteria](https://www.biorxiv.org/content/10.1101/2023.08.22.554312v2)”. PLOS Computational Biology, 20, 1



 

 

Avik Mukherjee, Yu-Fang Chang, Yanqing Huang, Jade Ealy, Mark Polk, and Markus Basan. 2024. “[Plasticity of Growth Laws Tunes Resource Allocation Strategies in Bacteria](https://www.biorxiv.org/content/10.1101/2023.08.22.554312v2)”. PLOS Computational Biology, 20, 1



 

 

 

- [ descriptionPublisher's Version](https://journals.plos.org/ploscompbiol/article?id=10.1371/journal.pcbi.1011735)
 
- [ descriptionPublisher's Version](https://journals.plos.org/ploscompbiol/article?id=10.1371/journal.pcbi.1011735)
 
 

Severin Schink, Mark Polk, Edward Athaide, Avik Mukherjee, Constantin Ammar, Xili Liu, Seungeun Oh, Yu-Fang Chang, and Markus Basan. 2024. “[Survival Dynamics of Starving Bacteria Are Determined by Ion Homeostasis for Maintaining Plasmolysis](/publications/energy-requirements-ion-homeostasis-determine-lifespan-starving-bacteria)”. Nature Physics



 

 

Severin Schink, Mark Polk, Edward Athaide, Avik Mukherjee, Constantin Ammar, Xili Liu, Seungeun Oh, Yu-Fang Chang, and Markus Basan. 2024. “[Survival Dynamics of Starving Bacteria Are Determined by Ion Homeostasis for Maintaining Plasmolysis](/publications/energy-requirements-ion-homeostasis-determine-lifespan-starving-bacteria)”. Nature Physics



 

 

 

- add\_circle do\_not\_disturb\_on Abstract
- [ descriptionPublisher's Version](https://doi.org/10.1038/s41567-024-02511-2)
- [ picture\_as\_pdfschink\_et\_al2024.pdf](/sites/g/files/omnuum9251/files/schink_et_al2024.pdf)
- [ picture\_as\_pdfsi\_schink\_et\_al2024.pdf](/sites/g/files/omnuum9251/files/si_schink_et_al2024.pdf)
- [ picture\_as\_pdfxuyouk2024.pdf](/sites/g/files/omnuum9251/files/xuyouk2024.pdf)
 
 The majority of microbes on earth, whether they live in the ocean, the soil or in animals, are not growing, but instead struggling to survive starvation[1](https://www.biorxiv.org/content/10.1101/2021.11.22.469587v1#ref-1)–[6](https://www.biorxiv.org/content/10.1101/2021.11.22.469587v1#ref-6). Some genes and environmental conditions affecting starvation survival have been identified[7](https://www.biorxiv.org/content/10.1101/2021.11.22.469587v1#ref-7)–[13](https://www.biorxiv.org/content/10.1101/2021.11.22.469587v1#ref-13)... 

 

 

- [ descriptionPublisher's Version](https://doi.org/10.1038/s41567-024-02511-2)
- [ picture\_as\_pdfschink\_et\_al2024.pdf](/sites/g/files/omnuum9251/files/schink_et_al2024.pdf)
- [ picture\_as\_pdfsi\_schink\_et\_al2024.pdf](/sites/g/files/omnuum9251/files/si_schink_et_al2024.pdf)
- [ picture\_as\_pdfxuyouk2024.pdf](/sites/g/files/omnuum9251/files/xuyouk2024.pdf)
 
 

Yanqing Huang, Avik Mukherjee, Severin Schink, Nina Catherine Benites, and Markus Basan. 2024. “[Evolution and Stability of Complex Microbial Communities Driven by Trade-Offs](/publications/evolution-and-stability-complex-microbial-communities-driven-trade-offs)”. Molecular Systems Biology, Pp. 1-9



 

 

Yanqing Huang, Avik Mukherjee, Severin Schink, Nina Catherine Benites, and Markus Basan. 2024. “[Evolution and Stability of Complex Microbial Communities Driven by Trade-Offs](/publications/evolution-and-stability-complex-microbial-communities-driven-trade-offs)”. Molecular Systems Biology, Pp. 1-9



 

 

 

- add\_circle do\_not\_disturb\_on Abstract
- [ descriptionPublisher's Version](https://www.embopress.org/doi/full/10.1038/s44320-024-00051-8)
- [ picture\_as\_pdfhuang-et-al-2024-evolutio...](/sites/g/files/omnuum9251/files/huang-et-al-2024-evolution-and-stability-of-complex-microbial-communities-driven-by-trade-offs.pdf)
 
 Microbial communities are ubiquitous in nature and play an important role in ecology and human health. Cross-feeding is thought to be core to microbial communities, though it remains unclear precisely why it emerges. Why have multi-species microbial... 

 

 

- [ descriptionPublisher's Version](https://www.embopress.org/doi/full/10.1038/s44320-024-00051-8)
- [ picture\_as\_pdfhuang-et-al-2024-evolutio...](/sites/g/files/omnuum9251/files/huang-et-al-2024-evolution-and-stability-of-complex-microbial-communities-driven-by-trade-offs.pdf)
 
 

 



### 2023

Avik Mukherjee, Jade Ealy, Yanqing Huang, Nina Catherine Benites, Mark Polk, and Markus Basan. 2023. “[Coexisting Ecotypes in Long-Term Evolution Emerged from Interacting Trade-Offs](https://www.nature.com/articles/s41467-023-39471-9)”. Nature Communications, 14, Pp. 3805



 

 

Avik Mukherjee, Jade Ealy, Yanqing Huang, Nina Catherine Benites, Mark Polk, and Markus Basan. 2023. “[Coexisting Ecotypes in Long-Term Evolution Emerged from Interacting Trade-Offs](https://www.nature.com/articles/s41467-023-39471-9)”. Nature Communications, 14, Pp. 3805



 

 

 

- add\_circle do\_not\_disturb\_on Abstract
- [ picture\_as\_pdfcoexistinglenski.pdf](/sites/g/files/omnuum9251/files/markusbasan/files/coexistinglenski.pdf)
 
 Evolution of complex communities of coexisting microbes remains poorly understood. The long-term evolution experiment on *Escherichia coli* (LTEE) revealed the spontaneous emergence of stable coexistence of multiple ecotypes, which persisted for more than... 

 

 

- [ picture\_as\_pdfcoexistinglenski.pdf](/sites/g/files/omnuum9251/files/markusbasan/files/coexistinglenski.pdf)
 
 

Shalaka Chitale, Wenxuan Wu, Avik Mukherjee, Herbert Lannon, Pooja Suresh, Ishan Nag, Christina M. Ambrosi, Rona S. Gertner, Hendrick Melo, Brendan Powers, Hollin Wilkins, Henry Hinton, Michael Cheah, Zachariah G. Boynton, Alexander Alexeyev, Duane Sword, Markus Basan, Hongkun Park, Donhee Ham, and Jeffrey Abbott. 2023. “[A Semiconductor 96-Microplate Platform for Electrical-Imaging Based High-Throughput Phenotypic Screening](/publications/semiconductor-96-microplate-platform-electrical-imaging-based-high)”. Nature Communications, 14, 7576



 

 

Shalaka Chitale, Wenxuan Wu, Avik Mukherjee, Herbert Lannon, Pooja Suresh, Ishan Nag, Christina M. Ambrosi, Rona S. Gertner, Hendrick Melo, Brendan Powers, Hollin Wilkins, Henry Hinton, Michael Cheah, Zachariah G. Boynton, Alexander Alexeyev, Duane Sword, Markus Basan, Hongkun Park, Donhee Ham, and Jeffrey Abbott. 2023. “[A Semiconductor 96-Microplate Platform for Electrical-Imaging Based High-Throughput Phenotypic Screening](/publications/semiconductor-96-microplate-platform-electrical-imaging-based-high)”. Nature Communications, 14, 7576



 

 

 

- add\_circle do\_not\_disturb\_on Abstract
- [ descriptionPublisher's Version](https://www.nature.com/articles/s41467-023-43333-9)
- [ picture\_as\_pdfnature\_comm.pdf](/sites/g/files/omnuum9251/files/markusbasan/files/nature_comm.pdf)
 
 High-content imaging for compound and genetic profiling is popular for drug discovery but limited to endpoint images of fixed cells. Conversely, electronic-based devices offer label-free, live cell functional information but suffer from limited spatial... 

 

 

- [ descriptionPublisher's Version](https://www.nature.com/articles/s41467-023-43333-9)
- [ picture\_as\_pdfnature\_comm.pdf](/sites/g/files/omnuum9251/files/markusbasan/files/nature_comm.pdf)
 
 

 



### 2022

Severin Josef Schink, Dimitris Christodoulou, Avik Mukherjee, Edward Athaide, Viktoria Brunner, Tobias Fuhrer, Gary Andrew Bradshaw, Uwe Sauer, and Markus Basan. 2022. “[Glycolysis/Gluconeogenesis/Specialization/in/Microbes/Is/Driven/by/Biochemical/Constraints/of/Flux/Sensing](/publications/substrate-specialization-microbes-driven-biochemical-constraints-dynamic)”. Molecular Systems Biology, 18, 1, Pp. e10704



 

 

Severin Josef Schink, Dimitris Christodoulou, Avik Mukherjee, Edward Athaide, Viktoria Brunner, Tobias Fuhrer, Gary Andrew Bradshaw, Uwe Sauer, and Markus Basan. 2022. “[Glycolysis/Gluconeogenesis/Specialization/in/Microbes/Is/Driven/by/Biochemical/Constraints/of/Flux/Sensing](/publications/substrate-specialization-microbes-driven-biochemical-constraints-dynamic)”. Molecular Systems Biology, 18, 1, Pp. e10704



 

 

 

- add\_circle do\_not\_disturb\_on Abstract
- [ descriptionPublisher's Version](https://www.embopress.org/doi/full/10.15252/msb.202110704)
- [ picture\_as\_pdfmolecular\_systems\_biology...](/sites/g/files/omnuum9251/files/markusbasan/files/molecular_systems_biology_-_2022_-_schink_-_glycolysis_gluconeogenesis_specialization_in_microbes_is_driven_by_biochemical.pdf)
 
 Central carbon metabolism is highly conserved across microbial species, but can catalyze very different pathways depending on the organism and their ecological niche. Here, we study the dynamic reorganization of central metabolism after switches between... 

 

 

- [ descriptionPublisher's Version](https://www.embopress.org/doi/full/10.15252/msb.202110704)
- [ picture\_as\_pdfmolecular\_systems\_biology...](/sites/g/files/omnuum9251/files/markusbasan/files/molecular_systems_biology_-_2022_-_schink_-_glycolysis_gluconeogenesis_specialization_in_microbes_is_driven_by_biochemical.pdf)
 
 

Severin Schink, Zara Gough, Elena Biselli, Mariel Garcia Huiman, Yu-Fang Chang, Markus Basan, and Ulrich Gerland. 2022. “[MetA Is a ‘thermal Fuse’ That Arrests Growth and Protects Escherichia Coli at Elevated Temperatures](https://www.sciencedirect.com/science/article/pii/S221112472201110X)”. Cell Reports, 40, 9, Pp. 111290



 

 

Severin Schink, Zara Gough, Elena Biselli, Mariel Garcia Huiman, Yu-Fang Chang, Markus Basan, and Ulrich Gerland. 2022. “[MetA Is a ‘thermal Fuse’ That Arrests Growth and Protects Escherichia Coli at Elevated Temperatures](https://www.sciencedirect.com/science/article/pii/S221112472201110X)”. Cell Reports, 40, 9, Pp. 111290



 

 

 

- add\_circle do\_not\_disturb\_on Abstract
- [ descriptionPublisher's Version](https://www.biorxiv.org/content/10.1101/2021.06.14.448417v2)
- [ picture\_as\_pdfthermal\_fuse.pdf](/sites/g/files/omnuum9251/files/markusbasan/files/thermal_fuse.pdf)
 
 Adaptive stress resistance in microbes is mostly attributed to the expression of stress response genes, including heat-shock proteins. Here, we report a response of *E. coli* to heat stress caused by degradation of an enzyme in the [methionine](https://www.sciencedirect.com/topics/biochemistry-genetics-and-molecular-biology/methionine) [biosynthesis](https://www.sciencedirect.com/topics/biochemistry-genetics-and-molecular-biology/anabolism) p... 

 

 

- [ descriptionPublisher's Version](https://www.biorxiv.org/content/10.1101/2021.06.14.448417v2)
- [ picture\_as\_pdfthermal\_fuse.pdf](/sites/g/files/omnuum9251/files/markusbasan/files/thermal_fuse.pdf)
 
 

Jeffrey Abbott, Avik Mukherjee, Wenxuan Wu, Tianyang Ye, Han Sae Jung, Kevin M. Cheung, Rona S. Gertner, Markus Basan, Donhee Ham, and Hongkun Park. 2022. “[Multi-Parametric Functional Imaging of Cell Cultures and Tissues With a CMOS Microelectrode Array](/publications/multi-parametric-functional-imaging-cell-cultures-and-tissues-cmos)”. Lab on a Chip



 

 

Jeffrey Abbott, Avik Mukherjee, Wenxuan Wu, Tianyang Ye, Han Sae Jung, Kevin M. Cheung, Rona S. Gertner, Markus Basan, Donhee Ham, and Hongkun Park. 2022. “[Multi-Parametric Functional Imaging of Cell Cultures and Tissues With a CMOS Microelectrode Array](/publications/multi-parametric-functional-imaging-cell-cultures-and-tissues-cmos)”. Lab on a Chip



 

 

 

- add\_circle do\_not\_disturb\_on Abstract
- [ descriptionPublisher's Version](https://pubs.rsc.org/en/content/articlelanding/2022/lc/d1lc00878a#!divCitation)
- [ picture\_as\_pdfabottetal2022.pdf](/sites/g/files/omnuum9251/files/markusbasan/files/abottetal2022.pdf)
 
 Electrode-based impedance and electrochemical measurements can provide cell-biology information that is difficult to obtain using optical-microscopy techniques. Such electrical methods are non-invasive, label-free, and continuous, eliminating the need for... 

 

 

- [ descriptionPublisher's Version](https://pubs.rsc.org/en/content/articlelanding/2022/lc/d1lc00878a#!divCitation)
- [ picture\_as\_pdfabottetal2022.pdf](/sites/g/files/omnuum9251/files/markusbasan/files/abottetal2022.pdf)
 
 

Severin Schink, Constantin Ammar, Yu-Fang Chang, Ralf Zimmer, and Markus Basan. 2022. “[Analysis of Proteome Adaptation Reveals a Key Role 1 of the Bacterial Envelope in Starvation Survival](https://www.embopress.org/doi/full/10.15252/msb.202211160)”. Molecular Systems Biology, 18, 12, Pp. e11160



 

 

Severin Schink, Constantin Ammar, Yu-Fang Chang, Ralf Zimmer, and Markus Basan. 2022. “[Analysis of Proteome Adaptation Reveals a Key Role 1 of the Bacterial Envelope in Starvation Survival](https://www.embopress.org/doi/full/10.15252/msb.202211160)”. Molecular Systems Biology, 18, 12, Pp. e11160



 

 

 

- add\_circle do\_not\_disturb\_on Abstract
 
 Bacteria reorganize their physiology upon entry to stationary phase. What part of this reorganization improves starvation survival is a difficult question because the change in physiology includes a global reorganization of the proteome, envelope, and... 

 

 

 

 



### 2021

Seungeun Oh, Changhee Lee, Wenlong Yang, Ang Li, Avik Mukherjee, Markus Basan, Chongzhao Ran, Wei Yin, Clifford J. Tabin, Dan Fu, X. Sunney Xie, and Marc W. Kirschner. 2021. “[Protein and Lipid Mass Concentration Measurement in Tissues by Stimulated Raman Scattering Microscopy](/publications/protein-and-lipid-mass-concentration-measurement-tissues-stimulated-raman)”. PNAS, 119, 17, Pp. e2117938119



 

 

Seungeun Oh, Changhee Lee, Wenlong Yang, Ang Li, Avik Mukherjee, Markus Basan, Chongzhao Ran, Wei Yin, Clifford J. Tabin, Dan Fu, X. Sunney Xie, and Marc W. Kirschner. 2021. “[Protein and Lipid Mass Concentration Measurement in Tissues by Stimulated Raman Scattering Microscopy](/publications/protein-and-lipid-mass-concentration-measurement-tissues-stimulated-raman)”. PNAS, 119, 17, Pp. e2117938119



 

 

 

- add\_circle do\_not\_disturb\_on Abstract
- [ descriptionPublisher's Version](https://doi.org/10.1073/pnas.2117938119)
- [ picture\_as\_pdfnori.pdf](/sites/g/files/omnuum9251/files/markusbasan/files/nori.pdf)
 
 Cell mass and chemical composition are important aggregate cellular properties that are especially relevant to physiological processes, such as growth control and tissue homeostasis. Despite their importance, it has been difficult to measure these... 

 

 

- [ descriptionPublisher's Version](https://doi.org/10.1073/pnas.2117938119)
- [ picture\_as\_pdfnori.pdf](/sites/g/files/omnuum9251/files/markusbasan/files/nori.pdf)
 
 

 



 

 

 

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